China (Mainland)
Chondroitinase AC CAS NO.9047-57-8
- Min.Order: 0 Metric Ton
- Payment Terms: T/T
- Product Details
Keywords
- Chondroitinase ABC
- Reagent
- diagnostic reagents
Quick Details
- ProName: Chondroitinase AC
- CasNo: 9047-57-8
- Application: Chondroitinase AC is useful in many ap...
- DeliveryTime: two weeks
- PackAge: stored in vials
- Port: Beijing
- ProductionCapacity: 1000 Metric Ton/Day
- Purity: ≥ 90% by reversed phase HPLC analysis
- Transportation: Air shipping
- LimitNum: 0 Metric Ton
Superiority
General Information
Synonyms: Chondroitin sulfate lyase, chondroitin sulfate eliminase
Gene Source: Native Flavobacterium heparinum
EC Number: 4.2.2.5
CAS Number: 9047-57-8
MDL Number: MFCD00130796
Catalyzed Reaction: Chondroitinase AC cleaves, via na elimination mechanism, sulfated and non-sulfated polysaccharide chains containing 1-4 linkages between hexosamines and glucuronic acid residues. The reaction yields oligosacchardie products (mainly disaccharides) containing unsaturated uronic acids which can be detected by UV spectroscopy at 232 nm. The enzyme is active on chondroitin sulfates A and C, chondroitin and hyaluronic acid, but is not active on dermatan sulfate (chondroitin sulfate B).
Substrate Specificity: Chondroiting sulfates A and C, chondroitin, hyaluronic acid. (The specific activity with chondroitin sulfate A is approx 1.5 times higher than the specific activity with chondroitin sulfate C.)
Details
Chondroitinase AC cleaves, via na elimination mechanism, sulfated and non-sulfated polysaccharide chains containing 1-4 linkages between hexosamines and glucuronic acid residues. The reaction yields oligosacchardie products (mainly disaccharides) containing unsaturated uronic acids which can be detected by UV spectroscopy at 232 nm. The enzyme is active on chondroitin sulfates A and C, chondroitin and hyaluronic acid, but is not active on dermatan sulfate (chondroitin sulfate B).
Substrate Specificity: Chondroiting sulfates A and C, chondroitin, hyaluronic acid. (The specific activity with chondroitin sulfate A is approx 1.5 times higher than the specific activity with chondroitin sulfate C.)